Selected Publications from the West Group
Peer Reviewed - Journal Publications
- Wood KJ, Bushell AR, Darby CR, Pearson TC, West LJ, Morris PJ: Mechanism of induction of transplantation tolerance using donor antigen and anti-CD4 monoclonal antibody. Transplantation Proceedings, 1991: 23(1 Pt 1): 133-134.
- Pearson TC, Bushell AR, Darby CR, West LJ, Morris PJ, Wood KJ: Lymphocyte changes associated with prolongation of cardiac allograft survival in adult mice using anti-CD4 monoclonal antibody. Clinical and Experimental Immunology, 1993: 92(2): 211-217.
- Pearson TC, Darby CR, Bushell A, West LJ, Morris PJ, Wood KJ: The assessment of transplantation tolerance induced by anti-CD4 monoclonal antibody in the murine model. Transplantation, 1993: 55(2): 361-367.
- West LJ, Morris PJ, Wood KJ: Fetal liver haematopoietic cells and tolerance to organ allografts. The Lancet, 1994: 343(8890): 148-149.
- Walker RE, McCrindle BW, Coles JG, West LJ: Clinical outcomes associated with conversion to tacrolimus-based immunosuppression in pediatric cardiac transplantation. Transplantation Proceedings, 1998: 30: 1116-17.
- Borenstein SH, Tao K, West LJ, Chamberlain JW: Extrathymic deletion of CD8+ alloreactive T cells in a transgenic T cell receptor model of neonatal tolerance. Transplantation, 2001: 72(11): 1807-1816.
- West LJ, Pollock-BarZiv SM, Dipchand AI, Lee KJ, Cardella CJ, Rebeyka IM, Benson LN, Coles JG: ABO-incompatible heart transplantation in infants. The New England Journal of Medicine, 2001: 344(11): 793-800. (article accompanied by editorial)
- Dipchand AI, Benson L, McCrindle BW, Coles J, West LJ: Mycophenolate Mofetil in paediatric heart transplant recipients: a single centre experience. Pediatric Transplantation, 2001: 5: 112-118.
- West LJ: Defining critical windows in the development of the human immune system. Human and Experimental Toxicology, 2002: 21(9-10): 499-505. Review.
- West LJ: Developmental aspects of immunomodulation: exploiting the immature immune system for organ transplantation. Transplant Immunology, 2002: 9: 149-153.
- West LJ, Tao K: Acceptance of third-party cardiac, but not skin allografts induced by neonatal exposure to semi-allogeneic lymphohematopoietic cells. American Journal of Transplantation, 2002: 2(8): 733-744.
- Holsapple MP, West LJ, Landreth KS: Species comparison of anatomical and functional immune system development. Birth Defects Research (Part B), 2003: 68: 321-334.
- Ogle BM, Cascalho M, Joao C, Taylor W, West LJ, Platt JL: Direct measurement of lymphocyte receptor diversity. Nucleic Acids Research, 2003: 31(22): e139.
- Pollock-BarZiv SM, Anthony SJ, Niedra R, Dipchand AI, West LJ: Quality of life and function following cardiac transplantation in adolescents. Transplantation Proceedings, 2003: 35: 2468-2470.
- Foreman C, Gruenwald C, West LJ: ABO-incompatible heart transplantation: a perfusion strategy. Perfusion, 2004: 19(1): 69-72.
- Holsapple MP, Paustenback DJ, Charnley G, West LJ, Luster MI, Dietert RR, Burns-Naas LA: Symposium summary: children's health risk - what's so special about the developing immune system? Toxicology and Applied Pharmacology, 2004: 199(1): 61-70.
- Borenstein SH, Tao KS, Hu N, West LJ, Chamberlain JW: Induction of xenogeneic neonatal tolerance to transgenic human leukocyte antigen class I grafts. Transplantation, 2004: 78(6): 844-852.
- Hofmann B, Tao K, Mai L, West LJ: Acceptance of related and unrelated cardiac allografts in neonatally-tolerized mice is cardio-specific and transferable by regulatory CD4+ T cells. Journal of Heart and Lung Transplantation, 2004: 23: 1069-76.
- Fan X, Ang A, Pollock-BarZiv SM, Dipchand AI, Ruiz P, Wilson G, Platt JL, West LJ: Donor-specific B cell tolerance after ABO-incompatible infant heart transplantation. Nature Medicine, 2004: 10(11): 1227-1233. (article accompanied by a ‘News and Views’ commentary)
- Yoshimitsu M, Sato T, Tao K, Walia J, Rasaiah VI, Sleep GT, Murray GJ, Poeppl AG, Underwood J, West LJ, Brady RO, Medin JA: Bioluminescent imaging of a marking transgene and correction of Fabry mice by neonatal injection of recombinant lentiviral vectors. Proceedings of the National Academy of Sciences, 2004: 101(48): 16909-14.
- Lobach NE, Pollock-BarZiv SM, West LJ, Dipchand AI: Sirolimus immunosuppression in pediatric heart transplant recipients: a single-center experience. The Journal of Heart and Lung Transplantation, 2005:24(2): 184-189.
- Pollock-BarZiv SM, Dipchand AI, McCrindle BW, West LJ: Randomized clinical trial of Tacrolimus- vs Cyclosporine-based immunosuppression in pediatric heart transplantation: preliminary results at 15-month follow-up. The Journal of Heart and Lung Transplantation, 2005: 24(2): 190-194.
- Fan X, Tyerman K, Ang A, Koo K, Parameswaran K, Tao K, Mai L, Lang H, West LJ: A novel tool for B cell tolerance research: characterization of mouse alloantibody development using a simple and reliable cellular ELISA technique. Transplantation Proceedings, 2005: 37: 29-31.
- Rodriguez RJ, Addonizio LJ, Lamour JM, Mital S, Mosca R, West LJ, Nova JC, Hsu DT: Pediatric heart transplantation across ABO blood type barriers: a case study. Progress in Transplantation, 2005: 15(2): 161-5. Review.
- West LJ: Targeting an antibody-mediated rejection in the setting of ABO-incompatible infant heart transplantation: graft accommodation vs. B cell tolerance. Current Drug Targets - Cardiovascular and Hematological Disorders, 2005: 5(3): 223-232.
- West LJ: ABO-incompatible heart transplantation: an alternative to improve the donor shortage in infants. Current Opinion in Organ Transplantation, 2005: 10(4): 364-368.
- Fan X, Ang A, Tao K, West LJ: Induction of human histo-blood group A antigen expression in mouse cells by gene therapy using lentiviral vectors harbouring human ABH-related glycosyltransferase genes. Transplantation Proceedings, 2005: 37(1): 265-267.
- Ogle BM, West LJ, Driscoll DJ, Strome SE, Razonable RR, Paya CV, Cascalho M, Platt JL: Effacing of the T cell compartment by cardiac transplantation in infancy. Journal of Immunology, 2006: 176: 1962-1967.
- West LJ, Karamlou T, Dipchand AI, Pollock-BarZiv SM, Coles JG, McCrindle BW: Impact on outcomes after listing and transplantation, of a strategy to accept ABO blood group-incompatible donor hearts for neonates and infants. The Journal of Thoracic and Cardiovascular Surgery, 2006: 131(2): 455-61.
- West LJ: B cell tolerance following ABO-incompatible infant heart transplantation. Transplantation, 2006: 81(3): 301-307.
- BarZiv SM, McCrindle BW, West LJ, Edgell D, Coles JG, VanArsdell GS, Bohn D, Perez R, Campbell A, Dipchand AI: Outcomes of pediatric patients bridged to heart transplantation from extracorporeal membrane oxygenation support. American Society for Artificial Internal Organs Journal, 2007: 53(1): 97-102.
- Zhou YQ, Bishay R, Feintuch A, Tao K, Golding F, Zhu W, West LJ, Henkelman RM: Morphological and functional evaluation of murine heterotopic cardiac grafts using ultrasound biomicroscopy. Ultrasound in Medicine and Biology, 2007: 33(6): 870-9.
- Pollock-BarZiv SM, McCrindle BW, West LJ, Manlhiot C, VanderVliet M, Dipchand AI: Competing outcomes after neonatal and infant wait-listing for heart transplantation. Journal of Heart and Lung Transplantation, 2007: 26(10): 980-5.
- Pollock-BarZiv SM, den Hollander N, Ngan BY, Kantor P, McCrindle B, Dipchand AI, West LJ: Pediatric heart transplantation in human leukocyte antigen sensitized patients: evolving management and assessment of intermediate-term outcomes in a high-risk population. Circulation, 2007: 116(11 Suppl): I172-8.
- Pollock-Barziv SM, McCrindle BW, West LJ, Dipchand AI: Waiting before birth: outcomes after fetal listing for heart transplantation. American Journal of Transplantation, 2008: 8(2): 412-8.
- Platt JL, Cascalho M, West LJ: Lessons from cardiac transplantation and infancy. Pediatric Transplantation, 2009: 13(7): 814-9.
- Dipchand AI, Pollock-BarZiv SM, Manlhiot C, West LJ, VanderVliet M, McCrindle BW: Equivalent outcomes for pediatric heart transplantation recipients: ABO-blood group incompatible versus ABO-compatible. American Journal of Transplantation, 2010: 10(2): 389-97.
- Laing B, Ross DB, Meyer SR, Campbell PC, Halpin AM, West LJ, Rebeyka IM: Glutaraldehyde treatment of allograft tissue decreases allosensitization following the Norwood procedure. Journal of Thoracic and Cardiovascular Surgery, 2010: 139(6): 1402-8.
- Urschel S, Campbell PM, Meyer SR, Larsen IM, Neubel J, Birnbaum J, Netz H, Tinckam K, Kauke T, Derkatz K, Coe JY, Platt JL, West LJ: Absence of donor-specific HLA antibodies after ABO-incompatible heart transplantation in infancy-Altered immunity or age? American Journal of Transplantation, 2010: 10(1): 149-56.
- Fan X, Lang H, Zhou X, Zhang L, Yin R, Maciejko J, Giannitsos V, Motyka B, Medin JA, Platt JL, West LJ: Induction of human blood group A-antigen expression on mouse cells, using lentiviral gene transduction. Human Gene Therapy, 2010: 21(7): 877-90.
- West LJ, Platt JL: And justice for all: consideration of ABO compatibility in allocation of hearts for infant transplantation. Circulation, 2010: 121(17): 1884-6.
- Meloncelli PJ, West LJ, Lowary TL: Synthesis and NMR studies on the ABO
histo-blood group antigens: synthesis of type III and IV structures and NMR
characterization of type I-VI antigens. Carbohydr Res, 2011: 346(12): 1406-26.
- West LJ: ABO-incompatible hearts for infant transplantation. Curr Opin Organ Transplant, 2011: 16(5): 548-54.
- West LJ: Antibodies and ABO-incompatibility in pediatric transplantation. Pediatr Transplant, 2011: 15(8): 778-83.
- Jeyakanthan M, West LJ: Donor-specific isohemagglutinins: measuring the
unknown. Am J Transplant, 2012: 12(4): 803-5.
- Urschel S, Larsen IM, Kirk R, Flett J, Burch M, Shaw N, Birnbaum J, Netz H, Pahl E, Matthews KL, Chinnock R, Johnston JK, Derkatz K, West LJ: ABO-incompatible heart transplantation in early childhood: An international multicenter study of clinical experiences and limits. J Heart Lung Transplant, 2013: 32(3): 285-92.
Books/Chapters in Books
- West LJ: Doctor of Philosophy thesis: Neonatal induction of tolerance to cardiac allografts. University of Oxford Press, Oxford, UK 1995.
- West LJ: Heart transplantation across blood group incompatibility. In: Transplant Team. Parkhurst Publishing (Novartis), Montreal, Quebec 1999.
- West LJ: Heart transplantation in children. In: Textbook of Transplantation (Ginns LC, Cosimi AB, Morris PJ, eds). Blackwell Science Inc, Boston 1999.
- West LJ: Crossing the ABO barrier in infant heart transplantation at the Hospital for Sick Children. In: Clinical Transplants, 2004: 243-252. (Cecka JM and Terasaki PI, Eds.) UCLA Immunogenetics Center, Los Angeles, California.
- West LJ, Shaddy RE, Balfour IC: Special immunologic issues in pediatric heart transplantation. International Society for Heart and Lung Transplantation (ISHLT) Pediatric Transplantation Monograph from the ISHLT Monograph Series, Vol 2. (Canter CE and Kirklin JK, Eds.) Elsevier Inc., 2007, Chpt. 4: 55-69.
- Kirklin JK, Mehra M, West LJ (Editors): International
Society for Heart and Lung Transplantation (ISHLT) Pediatric Transplantation Monograph from the ISHLT Monograph Series, Vol 4, Elsevier Inc, 2010.
- West LJ: ABO incompatible pediatric heart transplantation. Transplantation Index & Reviews, 2010, Vol. III, No. 2.
- Urschel S, West LJ: Pediatrics: Developmental Immunology. In: Textbook of Organ Transplantation, 2012 (Peacock J, Ed.) Wiley-Blackwell (in press).